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REJUVENATION REIMAGINED

Delivering fast results with
the greatest concentration of
growth factors in aesthetics.

Portrait of woman's face with flower petals in her hair

Purity built on scientific excellence

ariessence pure PDGF+ is a potent, proprietary, topical, post-procedural enhancement, which utilizes recombinant technology to produce a pure, sterile, pharmaceutical-grade PDGF combined with hyaluronic acid. HA acts to retain or increase moisture, as a skin conditioning agent, and as a contributor to a healthy skin barrier.

What makes ariessence
pure PDGF+ the best
choice for my patients?

A black and white photo of a provider applying ariessence pure PDGF+ to a woman

Proven and trusted.

Harnessing the only proven growth factor in aesthetics, ariessence is powered by PDGF, the same growth factor used in four separate FDA approved medical products with 28 yrs of therapeutic use. pure PDGF is now the next generation in skin rejuvenation.*

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Zero blood draw. Sterile.
Pure confidence.

Without a blood draw, ariessence is easy to use, simple to understand, and can be applied quickly. pure PDGF+ is incredibly predictable and consistent, with a well-documented safety profile, resulting in enhanced outcomes. That’s as patient friendly as it gets.

Black and white portrait of a smiling woman

Natural beauty, accelerated.

ariessence delivers faster results with superior potency due to the greatest concentration of growth factors in aesthetics. This simple, topical solution for post-procedural enhancement provides rapid results that your patients can see and feel.

FDA approval of these products was based on each product’s own formulation, controls, extensive safety and effectiveness data, including data derived from blinded, randomized, controlled human clinical trials (i.e., pivotal studies) which were conducted independently from ariessence pure PDGF+®.

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ariessence pure PDGF+ harnesses the power of nature’s most powerful growth factor for skin rejuvenation, PDGF-BB. The benefits of platelet-derived growth factor have been extensively studied by researchers. We utilize recombinant technology to produce a pure, sterile, pharmaceutical-grade product. And unlike products jammed with additives, ariessence pure PDGF+ only contains four ingredients: water, sodium acetate, hyaluronic acid, and sh-polypeptide-59 dimer.

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pure PDGF+ contains up to 300,000 times the growth factor concentration of competitive applications. This incredible potency means results may be obtained with fewer applications, leaving you with happier clients.

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Because ariessence pure PDGF+ is pharmaceutical grade, every application contains a consistent concentration. Unlike other products, pure PDGF+ does not rely on patient production of platelets. Because of this predictability, pure PDGF+ helps providers eliminate the guesswork in skin rejuvenation while giving patients a safe, consistent product, every time.

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PDGF is a widely studied growth factor. A recent clinical trial demonstrates pure PDGF to be safe and effective for post-procedural application in aesthetics. rhPDGF-BB is used in 4 FDA-approved medical treatments (GEM 21S®, Augment®, Augment® Injectable, and Regranex®) and over 5.5 million patients have been treated with pure PDGF products in the last 28 years.*

FDA approval of these products was based on each product’s own formulation, controls, extensive safety and effectiveness data, including data derived from blinded, randomized, controlled human clinical trials (i.e., pivotal studies) which were conducted independently from ariessence pure PDGF+®.

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pure PDGF

The science behind PDGF is supported by over 1,000 published papers and more than 100+ clinical trials, including an extensively-studied safety profile.

The Power of PDGF

A more natural look, from nature itself

There is growing interest in natural products and procedures—patient demand for restorative treatments and procedures is at an all time high. Patients are seeking enhanced confidence based on clear, natural-looking, healthier skin.

Growth factors like pure PDGF+ offer new and innovative approaches that work in harmony with the body’s natural abilities to rejuvenate. ariessence can be applied topically post-procedure to power natural skin rejuvenation.

See the power of nature itself.

Rapid results equal reduced downtime.
A better choice in any season.

ariessence pure PDGF+ provides results quickly, allowing patients much greater flexibility in scheduling treatments, dramatically expanding the opportunities for treatment.

When used after treatments including microneedling, RF microneedling, laser skin resurfacing, and peels, ariessence pure PDGF+ can enhance your patient’s results and reduce downtime.

Consider ariessence—and the procedures it enhances—as your 365 days-a-year option.

Evolutionary solution.
Revolutionary results.

As a post-procedure topical application, ariessence pure PDGF+ is the ideal enhancement for a wide range of rejuvenative, aesthetic treatments.

Providers & patients report:

  • Reduction of post-procedure down time
  • Noticeable improvement in the appearance of glowing skin
  • Improved tone and texture in the appearance of the skin

ariessence applied post-microneedling

Portrait of woman before microneedling

Before
(baseline)

Portrait of woman post-microneedling, immediately after

Immediately
post-procedure

Portrait of woman post-microneedling, 1 day after

1 day
post-procedure

Portrait of woman before microneedling

Before
(baseline)

Portrait of woman post-microneedling, immediately after

Immediately
post-procedure

Portrait of woman post-microneedling, 1 day after

1 day
post-procedure

Courtesy of Melissa McCartney, Master Aesthetician

ariessence applied post-microneedling

Portrait of man before microneedling

Before
(baseline)

Portrait of man post-microneedling, immediately after

Immediately
post-procedure

Portrait of man post-microneedling, 1 hour after

1 hour
post-procedure

Portrait of man post-microneedling, 1 day after

1 day
post-procedure

Portrait of man post-microneedling, 7 days after

7 days
post-procedure

Courtesy of Amanda Biradi, Advanced Nurse Injector

ariessence applied post-microneedling

Portrait of woman before microneedling

Before
(baseline)

Portrait of woman post-microneedling, 1 hour after

1 hour
post-procedure

Portrait of woman post-microneedling, 1 day after

1 day
post-procedure

Courtesy of Amanda Biradi, Advanced Nurse Injector

ariessence applied post-BBL MOXI

Portrait of woman before microneedling

Before
(baseline)

Portrait of woman post-microneedling, immediately after

Immediately
post-procedure

Portrait of woman post-microneedling, 7 days after

7 days
post-procedure

Courtesy of Jennifer DeMaio MSN, FNP-C, CANS

ariessence applied post-BBL MOXI

Portrait of woman post-microneedling, immediately after

Immediately
post-procedure

Portrait of woman post-microneedling, immediately after

Immediately
post-procedure

Portrait of woman post-microneedling, immediately after

Immediately
post-procedure

Portrait of woman post-microneedling, 7 days after

7 days
post-procedure

Portrait of woman post-microneedling, 7 days after

7 days
post-procedure

Portrait of woman post-microneedling, 7 days after

7 days
post-procedure

Courtesy of Jennifer DeMaio MSN, FNP-C, CANS

ariessence applied post-HALO™/BBL

Portrait of woman before microneedling

Before
(baseline)

Portrait of woman post-microneedling, immediately after

Immediately
post-procedure

Portrait of woman post-microneedling, 1 day after

1 day
post-procedure

Portrait of woman post-microneedling, 3 days after

3 days
post-procedure

Courtesy of Stephanie Smith, FNP-C, CANS, LE

pure PDGF applied post-RF microneedling

Portrait of woman post-microneedling, immediately after

Immediately
post-procedure

Portrait of woman post-microneedling, 30 days after

30 day
post-procedure

Courtesy of Michael Gold, MD

Portrait of woman post-microneedling, immediately after

Immediately
post-procedure

Portrait of woman post-microneedling, 30 days after

30 day
post-procedure

Courtesy of Michael Gold, MD

Lynch SE, Huxel ST, Bond R, Biron J, Gold M. Recombinant Pure PDGF Improves Aesthetic Results and Patient Satisfaction Following RF Microneedling: A Prospective, Randomized, Controlled Clinical Trial. Journal of Cosmetic Dermatology. 2025 Sep;24(9):e70425. DOI: 10.1111/jocd.70425

Trust the science.
Believe in the results.

I absolutely love the outcomes I have seen using ariessence. We have used it post microneedling with radiofrequency and MOXI. Our patients presented with decreased post-procedure redness. We are no longer using exosomes and using only ariessence for these procedures.

Jennifer DeMaio
MSN, FNP-C, CANS
FACE Aesthetic Institute

My patients feel like their skin improved a little quicker than usual and are so far happy with the results. I am excited to see the continued progression.

Sarah Safa
MS, PAC
Refined Aesthetics

Both myself and our entire team of nurses, nurse practitioners and aestheticians have been utilizing ariessence pure PDGF since its launch in 2024. We have been impressed not only with the ease of application, but also the powerful healing abilities we’ve observed in patients receiving ablative laser and device procedures, along with microneedling

Dawn Sagrillo
MSN, AGNP-BC, APNP, CANS
Refresh Aesthetics Center

I love the ease of use with ariessence. It eliminates the blood draw needed for PRP treatments. I know that I’m getting a pure and consistent product each time with predictable results. Pure PDGF is a game changer for me and my clients.

Lori Phoenix
RN

It requires no blood draw, no concerns about the age or health of the patient, and has a much higher level of growth factor. For these reasons, ariessence pure PDGF+ is a huge win and I believe it is a no-brainer to bring it into every aesthetic practice.

Dr. Missy Clifton
Premier Dermatology

Using ariessence pure PDGF+ has transformed our patient experience post-ablative laser treatments. The application process is easy, allowing for seamless integration into our treatment protocols, and all without blood draw.

Sarah Safa P.A.
Refined Aesthetics

Purity you can trust.
Natural-looking skin they can see and feel.

ariessence pure PDGF+ is applied to a woman's face

In the aesthetics market, no post-aesthetic procedure product enables the level of time-tested success that is possible with pure PDGF+. If you’re looking to add a PURE, POTENT, PREDICTABLE, and PROVEN approach to skin rejuvenation to your practice, look no further than ariessence pure PDGF+.

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ariessence pure PDGF+
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